## Malaria RDT product testing: interactive guideThis interactive guide is designed to help select malaria RDTs with the specific performance characteristics required by national malaria control programmes, based on the results of the WHO-FIND malaria RDT product testing programme, Rounds 1-8. |

Choose the parameters to display by clicking on the buttons below:

Panel detection score, 200 parasites/μl
Panel detection score, 2000-5000 parasites/μl
False positive ratesInvalid rate
Heat stability (Pf), 200 parasites/μl
Heat stability (Pf), 2000 parasites/μl
Heat stability (Pv), 200 parasites/μl
Heat stability (Pv), 2000 parasites/μl
Test lines: order and target antigens
Blood volume
Buffer volume
Reading time
Protocol group
Meets WHO procurement criteria

Table View | Chart View (select products to compare by clicking, only compatible with ~10 products) |

Product | Manufacturer | Catalogue No | Panel detection score (%) | False positive rates (%) | Invalid rate (%)^{l} |
Positive test results (%) for P. falciparum (Pf line) at 200 parasites/μl. Lots 1 and 2 combined |
Positive test results (%) for P. falciparum (Pan line) at 200 parasites/μl. Lots 1 and 2 combined |
Positive test results (%) for P. falciparum (Pf line) at 2000 parasites/μl. Lots 1 and 2 combined |
Positive test results (%) for P. falciparum (Pan line) at 2000 parasites/μl. Lots 1 and 2 combined |
Positive test results (%) for P. vivax (Pv line) at 200 parasites/μl. Lots 1 and 2 combined |
Positive test results (%) for P. vivax (Pan line) at 200 parasites/μl. Lots 1 and 2 combined |
Positive test results (%) for P. vivax (Pv line) at 2000 parasites/μl. Lots 1 and 2 combined |
Positive test results (%) for P. vivax (Pan line) at 2000 parasites/μl. Lots 1 and 2 combined |
Test lines | Blood volume (μl) | Buffer volume (nrs of drops) | Reading time (minutes) | Protocol Group | Product meets WHO procurement criteria | ID | ||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|

200 parasites/μl, P. falciparum samples^{a, c} |
200 parasites/μl, P. vivax samples^{a, d} |
2000 or 5000 parasites/μl, P. falciparum samples^{a, c} |
2000 or 5000 parasites/μl, P. vivax samples^{a, d} |
200 parasites/μl, P. falciparum samples (false positive non Pf infection)^{e} |
2000 or 5000 parasites/μl, P. falciparum samples (false positive non Pf infection)^{g} |
200 parasites/μl, P. vivax samples (false positive Pf infection)^{f} |
2000 or 5000 parasites/μl, P. vivax samples (false positive Pf infection)^{h} |
Total. Clean negative samples. False positive Plasmodium spp. infection^{b,i} |
Baseline | 35℃ | 45℃ | Baseline | 35℃ | 45℃ | Baseline | 35℃ | 45℃ | Baseline | 35℃ | 45℃ | Baseline | 35℃ | 45℃ | Baseline | 35℃ | 45℃ | Baseline | 35℃ | 45℃ | Baseline | 35℃ | 45℃ | 1st (closest to control line) | 2nd | 3rd (Furthest from control line) | Min. | Max. |

**Notes:**

^{a} A sample is considered detected only if all RDTs from both lots read by the first technician, at minimum specified reading time, are positive

^{b} Rate of positive test results for malaria when the results should have been negative.

^{c} Round 1, n=79; Round 2, n=100; Round 3, n=99; Round 4, n=98; Round 5, n=100; Round 6, n=100; Round 7, n=100; Round 8, n=100

^{d} Round 1, n=20; Round 2, n=40; Round 3, n=35; Round 4, n=34; Round 5, n=35; Round 6, n=35; Round 7, n=35; Round 8, n=35

^{e} For combination tests, Pan or Pv line, only, positive indicates a false positive non P. falciparum infection. The number in parentheses indicates the total number of tests,
being by default: Round 1 n=316; Round 2, n=400; Round 3, n=396; Round 4, n=392; Round 5, n=400; Round 6, n=400; Round 7, n=400; Round 8, n=400

^{f} Pf line positive indicates a false positive P. falciparum infection. The number in parentheses indicates the total number of tests, being by default:
Round 1, n=80; Round 2, n=160; Round 3, n=140; Round 4, n=136; Round 5, n=140; Round 6, n=140; Round 7, n=140; Round 8, n=140

^{g} For combination tests, Pan or Pv line, only, positive indicates a false positive non-P. falciparum infection. The number in parentheses indicates the total number of tests, being by default:
Round 1, n=158, Round 2, n=200; Round 3, n=198; Round 4, n=196; Round 5, n=200; Round 6, n=200; Round 7, n=200; Round 8, n=200

^{h} Pf line positive indicates a false positive P. falciparum infection. The number in parentheses indicates the total number of tests, being by default:
Round 1, n=40; Round 2, n=80, Round 3, n=70; Round 4, n=68; Round 5, n=70; Round 6, n=70; Round 7, n=70; Round 8, n=70

^{i} Round 1, n=168; Round 2, n=200; Round 3, n=200; Round 4, n=232; Round 5, n=236; Round 6, n=208; Round 7, n=220; Round 8, n=208

^{j} Product resubmission, results from most recent round of testing replace previous results. Refer to Table S1 of the most recent report of Product Testing results (below).

^{k} PDS presented in the table is based on a positive Pf test line (either HRP2 or Pf-pLDH). The results in brackets are the PDS based alone on HRP2 and Pf-pLDH test lines, respectively

^{l} Round 1, n=954; Round 2, n=1240; Round 3, n=1204; Round 4, n=1192; Round 5, n=1214; Round 6, n=1210; Round 7, n=1210; Round 8, n=1210

^{n} ARKRAY Healthcare Pvt. Ltd. was formerly Span Diagnostics Ltd.

^{p} PDS presented in the table is based on one of the positive test lines (either Pan-pLDH or Pv-pLDH). For test line specific results refer to the tables and annexes in the full reports.

^{q} A division of Abbott Laboratories Inc.

Complete results of the WHO-FIND malaria RDT product testing programme (2018)